Innovations in the Diagnosis and Treatment of Left Ventricular Hypertrophy with Repolarization Abnormality

Cardiac Rhythm
5 min readApr 16, 2024

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In cases of left ventricular hypertrophy, better known as LVH, you’ll find that one of the lower chambers of the heart, usually the left one and hence the name, has become unusually thick. It therefore makes it difficult for the heart to carry out its work. This condition can sometimes be accompanied by a wide QRS on its ECG, which is usually caused by abnormal repolarization. That being said, we’ll take a look at how innovation is changing the diagnosis and treatment of this heart defect.

Ultraportable ECG patches for LVH monitoring

If you’ve worked with patients diagnosed with LVH, you may have realized that the preliminary stages of the condition have no visible symptoms. In fact, it’s completely possible for the patient to feel perfectly fine for the first few years, with discomforts becoming much more visible later on.

That’s where ultraportable ECG patches become necessary during routine health checkups. These can help you regularly assess the heart’s structural integrity so that you can watch out for unusual thickness around the left ventricle and other areas as well.

With some ECG patch technologies, you can get a continuous single-lead ECG signal for about 2 weeks on a single charge. In some cases, these devices can lay dormant and only become active when the patient experiences a symptom, which can help further increase its battery span.

These technologies prove particularly superior to traditional Holter monitoring, according to a PubMed study, where researchers found a diagnostic yield of over 63%, compared to Holter monitoring. which usually falls below 50%

Faros biosensor for real-time data gathering

Before an accurate diagnosis can be made about LVH with repolarization abnormality, the technician needs ample data about the condition over a set period. Cardiac Rhythm’s Faros biosensor provides an innovative web-enabled device to make that possible.

This device doubles up as a two-in-one solution, enabling both long- and short-term monitoring. It provides a non-invasive way for physicians to track the heart’s activity in real-time and provide the data that is necessary to identify LVH early such as:

1.Heart rate trend
2.Pause
3.P-wave analysis
4.QRS morphology and so on.

All in all, this biosensor can also help to provide important ECG data for diagnosis. For instance, you can get consistent information about the amplitude of the R wave in a VL. If it proves to be larger than 12 mm, then this might be an indication of LVH. This method is called the Modified Cornell Criteria, and of course, there are alternative ways to arrive at a diagnosis. No matter the strategy, these biosensors can provide the data that you need to get there.

AI-driven LVH diagnostics

With so much big data to work with, it can become a tricky affair to diagnose left ventricular hypertrophy with repolarization abnormality. Yet there’s a need for you to score it accurately and quickly while considering appropriate summations of the S wave and R wave across various leads and using this result to determine the sensitivity of the LVH.

In a nutshell, diagnosing LVH is not always a walk in the park, but here to lighten the load are AI-driven arrhythmia diagnostic platforms. These leverage the power of machine learning to help the scorer analyze an ECG report and draw more meaningful and accurate conclusions from the data available. Besides improving diagnostic turnaround time for ECG, this can also help to elevate diagnostic yield.

Cloud patient care platforms for self-management

Once LVH with repolarization abnormality has been diagnosed, it’s now time for treatment, and that’s where cloud patient care platforms like that offered by Cardiac Rhythm can be a game-changer. With patient and physician portals, patients with LVH have a direct line of access to physicians and their own data, and this can help enforce self-management of the condition.

It is also important to note that LVH is usually treated via medications, namely ACE inhibitors, which go a long way to alleviate the strain on the heart by reducing blood pressure. With these patient-centric care platforms, it becomes easier for patients to receive their prescriptions and treatment regimens directly from the doctor online. Additionally, physicians may also be able to use this medium as a channel through which they can enforce medication adherence.

All in all, these cloud platforms can have the following positive effects on the treatment of LVH by:

1.Providing ready access to medical records
2,Enabling digital check-ins & appointment reminders
3.Improving patient and doctor coordination
4.Providing data for improved & continuous decision-making

With the condition often caused by the heart overworking, these portals can help physicians understand the unique underlying problem for the patient so that it can be dealt with once and for all.

TAVR as a surgical alternative

Left ventricular hypertrophy is typically caused by unusually high blood pressure, and one of the driving forces can be the aortic valve. When it narrows for one reason or the other, it can require that the heart works a lot harder to get blood flowing through the aorta, which naturally increases the strain on the left ventricular muscles.

In such cases, surgery has always been the answer. However, we’re noticing a new innovation in place of traditional surgery for LVH called transcatheter aortic valve replacement, or TAVR for short. In both cases, a man-made valve is put in place of the aortic valve, however, in the case of TAVR, a balloon catheter is used to deliver the replacement as opposed to direct implantation via open-heart surgery.

According to reports we sampled from various news sources, by 2025, TAVR will be the standard solution in aortic valve replacements with the data showing that it will be used in 3 out of 4 such cases.

Raising the bar with LVH innovations

Left ventricular hypertrophy today affects about 20% of the population, according to a report by Cleaveland Clinic. It is a condition that continues to spread due to rising cases of obesity and high blood pressure. For this reason, it’s important that healthcare facilities and patients alike embrace the latest technologies that can help us improve the diagnosis and treatment of LVH with repolarization abnormality. From cloud-based, self-care platforms to intelligent biosensors, there are a lot of innovative options that can help us with this fight. If you’re on the hunt for first-grade cardiac remote patient monitoring solutions, be sure to reach out to Cardiac Rhythm today.

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Cardiac Rhythm
Cardiac Rhythm

Written by Cardiac Rhythm

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Cardiac Rhythm’s revolutionary pay-per-use heart performance monitor sets a new standard in patient&s compliance and diagnostic yield(https://www.cardiacrhythm)

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